A recent Article in Medical X press stated that Scientists have found a new link between diabetes and Alzheimer’s:  The research is published in the May 4, 2015 The Journal of Clinical Investigation.

While many earlier studies have pointed to diabetes as a possible contributor to Alzheimer’s, the new study – in mice – shows that elevated glucose in the blood can rapidly increase levels of , a key component of brain plaques in Alzheimer’s patients. The buildup of plaques is thought to be an early driver of the complex set of changes that Alzheimer’s causes in the brain.


The researchers also are investigating how changes caused by increased glucose levels affect the ability of regions to network with each other and complete cognitive tasks.

Meanwhile another Article in Medical X press found that “Low sugar uptake in brain appears to exacerbate Alzheimer’s disease.”

A deficiency in the protein responsible for moving glucose across the brain’s protective blood-brain barrier appears to intensify the neurodegenerative effects of Alzheimer’s disease, according to a new mouse study from the Keck School of Medicine of the University of Southern California (USC).


Glucose is the brain’s main energy source, and GLUT1 helps move it across the blood-brain barrier, a cellular layer that prevents entry of blood and pathogens into the brain. Previous research has shown diminished glucose uptake in the brain among individuals at genetic risk for Alzheimer’s disease, with a positive family history, and/or who develop the disease but show mild or no cognitive impairment. {Emphasis added.}

Are we confused yet?  Too much glucose can exacerbate the build up of plaque while the inability of delivering glucose to the brain intensifies the degenerative effects of Alzheimer;s disease.

Sounds like a double edge sword which can be blunted by a Ketogenic diet.  Then you reduce the bodies dependency on and reaction to glucose, while Ketones provide an alternate source of energy for the brain.  A win-win situation.